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Fallon, P, Kerr ,W, Gentry, T, Balber, A, Ludeman, S, Storms, R, Smith, C. Hematopoietic progenitors which express high levels of aldehyde dehydrogenase can be counted and enriched from mobilized peripheral blood. British Journal of Hematology. 122:99-108, 2003. |
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Rissieri DA, Talbot JT, Long GW, Vredenburgh JW, Gasparetto C, Smith C, Colvin M, Adams D, Morris A, Dodge R, Loftis J, Waters-Pick B, Reese M, Carawan H, Chao N. . 4-hydroperoxycyclophosphamide purged peripheral blood stem cells for autologous transplantation in patients with acute myeloid leukemia. Biology of Blood and Marrow Transplantation. 9:183-188, 2003. |
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Smith, C. Hematopoietic stem cells and hematopoiesis. Cancer Control. 10:9-16, 2003. |
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Long, GW, Maden, B, Kurtzberg, J, Rubinstein, P, Gasparetto, C, Rizzieri, D, Smith, C, Vredenburgh, J, Halperin, E, Broadwater, G, Niedzweiki, D, Chao, NJ. Unrelated umbilical cord blood transplantation in adult patients. Biology of Blood and Marrow Transplantation. 9:772-780, 2003. |
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Nimmanapalli, R, Fiuno, L, Bali, P, Gasparetto, M, Glozak, M, Tao, J, Moscinski, L, Smith, C, Wu, J, Jove, R, Atadja, P, Bhalla, K. Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells. Cancer Research. 63:5126-35, 2003. |
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Gasparetto C, Gasparetto M, Vredenberg J, Long G, Rizzieri D, Chao N, Loftis J, Smith C. Mobilization of dendritic cells from patients with breast cancer using Flt-3-ligand in combination with G-CSF or GM-CSF. Cytokine. , 2002. |
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Nishimura J, Ware RE. The hematopoietic defect in PNH is not due to defective stroma or abnormal interactions between bone marrow progenitor cells and stroma. Blood Cells, Molecules and Diseases. 29, 2002. |
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Ohkubo T, Barcena A, Smith C, Harrison MR, Muench M. High efficiency retroviral transduction of fetal liver CD38-CD34++ cells: Implications for in utero and ex utero gene therapy. Fetal Diagnosis and Therapy. 16(5):299-307, 2001. |
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Rice H, Storms R, Smith C, Flake AW. Hematopoietic stem cells: basic concepts and applications to surgical research. Surgical Research. :207-214, 2001. |
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Elwood N, Smith C. Retroviral vector gene transfer into hematopoietic stem cells: an overview. Leukemia and Lymphoma. 41:p1-18, 2001. |
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Nishimura J, Rosse WF, Phillips K, Smith C. Retroviral vector gene transfer of the pig-A gene into hematopoietic cells affected by paroxysmal nocturnal hemoglobinuria. Blood,. 97:p3004-3010, 2001. |
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McGaughey DS, Nikcevich DA, Long GD, Vredenburgh JJ, Rizzieri D, Smith CA, Broadwater G, Loftis JS, McDonald C, Moffiss AK, Floz RF, Chao NF. Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. Biol Blood and Marrow Transplant. 7:274-278, 2001. |
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Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Field SJ, Thompson MA, Ynag H, Fujiwara Y, Greenberg ME, Orkin S, DeGregori J, Smith C, Nevins J. Myc requires distinct E2F proteins to induce S phase and apoptosis. Molecular Cell. 8:105-113, 2001. |
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Storms B, Goodel P, Mulligan R, Smith C. Hoechst dye efflux relveals a novel CD7+CD34-Lin - lymphoid progenitor in human umbilical cord blood. Blood. 92:2125-33, 2000. |
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Howrey R, Smith C. Retroviral vector gene transfer into human erythroid precursors generated in-vitro. Gene Therapy. 7:215-220, 2000. |
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Rempell R, Storms R, Smith C, Nevins J. An E2F4 knockout mouse has abnormalities of growth and development in multiple tissues including the gut and the hematopoietic system. Molecular Cell. 6:293-306, 2000. |
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Lan N, Rooney B, Lee SW, Howrey R, Smith C, Sullenger B. Enhancing RNA repair efficiency by combining trans-splicing ribozyme that recognize different accessible sites on a target RNA. Molecular Therapy. 2:p245, 2000. |
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Howry R, Smith C. Retroviral vector gene transfer into human erythroid stem cells using a novel fluorescent substrate for aldehyde dehydrogenase. Proceedings of the National Academy of Science. 96:9118-23, 1999. |
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Castellino S, Smith C. Gene marking of ex-vivo expanded human umbilical cord blood megakaryocyte progenitors, Biology of Blood and Marrow Transplantation. 5:215-221, 1999. |
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Linn WC, Moore J, Smith C. gd-T-cell lymphoma in a renal transplant recipient. Leukemia and Lymphoma. 33:377-384, 1999. |
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Gentry T, Smith C. Retroviral vector gene transfer into CD34+CD38-33- umbilical cord blood cells. Experimental Hematology. 27:1244-1254, 1999. |
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Storms R, Trujillo A, Shah L, Ludeman S, Colvin M, Smith C. Enrichment of human hematopoietic stem cells using a novel fluorescent substrate for aldehyde dehydrogenase. Proceedings of the National Academy of Science. 96:9118-9123, 1999. |
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McCowage GB, Ruddoll T, Phillips K, Hull S, Gilboa E, Smith C. Multiparameter fluorescence activated cell sorting analysis of retroviral vector gene transfer into primitive umbilical cord blood cells. Experimental Hematology. 26:288-298, 1998. |
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Laughlin MJ, Rizzieri D, Smith C, Moore JO, Lilly S, Martin P, Carrier C, Stevens CE, Rubinstein P, Kurtzberg J. Engraftment and reconstitution of immune function post -unrelated cord blood transplant in an adult with acute lymphocytic leukemia. Leukemia Research. 22(3):215-9, 1998. |
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Lilly S, Miralles D, Mann K, Lyerly HK, Smith C. AIDS related malignancies. Annals of Medicine. 30:323-344, 1998. |
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Nishimura J, Kinoshita T, Smith C, Kitano K, Hoffman S, Burnette A, Inoue N, Machii T, Gilboa E, Kurtzberg J, Kitani T, Takeda J, Rosse WF. Paroxysmal nocturnal hemoglobinuria: molecular pathogenesis and novel therapeutic approaches. Hematopathology and Molecular Hematology. 11(3&4):119-146, 1998. |
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Miralles D, Smith C, Wichard LP, Morse M, Kostyu D, Haynes B, Patel D. CD34+CD38- umbilical cord blood cells develop into dendritic cells on human thymic stromal layers and micronodules. Journal of Immunology. 160:3290-3298, 1998. |
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Ware RE, Nishimura J, Smith C, Rosse W, Howard T. Resistance to apoptosis in paroxysmal nocturnal hemoglobinuria is not related to the pig-A gene mutation or surface expression of GPI-linked proteins. Blood. 92:2541-2550, 1998. |
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Smith C, Miralles D. Cytoreductive therapy, bone marrow transplantation and HIV infection. AIDS Research and Human Retroviruses. 14:1305-1313, 1998. |
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Lee N, Howrey R, Lee SW, Smith C, Sullenger B. Trans-splicing mediated repair of hemoglobinS to hemoglobinA. Science. 280:1593-1596, 1998. |
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Morris M, Zhou LJ, Tedder T, Lyerly HK, Smith C. Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte macrophage colony stimulating factor, interleukin-4, and tumor necrosis factor for use in cancer immunotherapy. Annals of Surgery. 226:6-16, 1997. |
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Rudoll T, Phillips K, Lee SW, Gaspar O, Gilboa E, Smith C. High efficiency retroviral vector mediated gene transfer into human peripheral blood CD4+ T-lymphocytes. Gene Therapy. 3(8):695-705, 1996. |
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Phillips K, Gentry T, McCowage G, Gilboa E, Smith C. Cell surface markers for assessing gene transfer in human hematopoietic cells. Nature Medicine. 2(10):1154-1157, 1996. |
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Lee SW, Gilboa E, Smith C. Inhibition of HIV-1 with RNA decoys. Advanced Drug Delivery Reviews. 17(3):369-371, 1996. |
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Kurtzberg JK, Laughlin M, Graham ML, Smith C, Olson JF, Casey JR, Carrier C, Stevens C, Rubenstein P. Transplantation of HLA-matched and partially mismatched stored placental blood-a viable alternative source of hemopoietic stem cells for unrelated transplantation. New England Journal of Medicine. 335(3):157-166, 1996. |
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Lee SW, Smith C, E Gilboa. Inhibition of HIV-1 with a potent trans-activation response element (TAR) decoy. International Antiviral News. 4(3):39-41, 1996. |
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Smith C, Lee SW, Gallardo H, Wong E, Page K, Gaspar O, Gilboa E. Protection of human T-cells from HIV following adeno-associated viral vector mediated gene transfer of RNA decoys. Antiviral Research. 32:99-115, 1996. |
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Lee SW, Gilboa E, Smith C. Inhibition of HIV-1 with minimal RRE decoys. International Antiviral News. 3:p.89, 1995. |
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Vieweg J, Boczkowski D, Roberson KM, Edwards DW, Philip M, Philip R, Rudoll T, Smith C, Robertson C, Gilboa E. Efficient gene transfer with adeno-associated virus-based plasmids complexed to cationic liposomes for gene therapy of human prostate cancer. Cancer Research. 55(11):2366-72, 1995. |
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Lee SW, Smith C, Gallardo H, Gilboa E. Inhibition of HIV by highly expressed trans-activating response RNA decoys. Gene Therapy. 2:p377, 1995. |
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Bohnlein E, Smith C, Marasco W. Gene therapy for HIV infection In, HIV: A Practical Approach.. IRL Press at Oxford University Press. , 1995. |
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Gasparetto C, Smith C, Firpo M, Gillio A, O'Reilly RJ, Moore MAS. Dyshematopoiesis in combined immunodeficiency associated with congenital neutropenia. American Journal of Hematology. 45:p.63, 1994. |
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Gilboa E, Smith C. Gene therapy for infectious diseases: The HIV model. Trends in Genetics. 10:p.139, 1994. |
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Gasparetto C, Smith C, Gillio A, Moore MAS, O'Reilly RJ. Enrichment of peripheral blood stem cells using in-vivo cytokine administration in a primate model. Bone Marrow Transplantation. 14:p 717, 1994. |
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Lee SW, Gallardo H, Gilboa E, Smith C. Inhibition of HIV-1 in human T-Cells by a potent RRE decoy comprised of the 13 nucleotide long minimal rev binding domain. Journal of Virology. 68:p.8254, 1994. |
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Smith C, Meunch MO, Gilboa E, Moore MAS. Development of a lacZ Marked WEHI-3B D+ Murine leukemic cell line as an in-vivo model of acute non-lymphocytic leukemia.. Leukemia. 7:p.310, 1993. |
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Bordignon C, Mavillo F, Ferrari G, Servida P, Ugazio AG, Notarangelo LD, Giloba E, Rossini S, O'Reilly RJ, Smith CA, et al. Transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID. Human Gene Therapy. 4:513, 1993. |
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Smith C. Retroviral Vector-Mediated Gene Transfer into Hematopoietic Cells: Prospects and issues. Journal of Hematotherapy. 1:p.155, 1992. |
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Smith C, Gasparetto C, Collins N, Gillio A, Meunch M, O'Reilly RJ, Moore MAS. Partial purification and characterization of a human Pre-CFU-GM progenitor population. Blood. 77:p.2122, 1991. |
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Sullenger B, Lee T, Smith C, Ungers G, Gilboa E. Expression of chimeric tRNA-Antisense transcripts renders nih 3t3 cells highly resistant to maloney murine leukemia virus replication. Molecular and Cellular Biology. 10:p.6152, 1990. |
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Bordignon C, Yu SF, Smith C, Hantzopoulos P, Ungers G, O'Reilly RJ, Gilboa E. High level expression of retroviral mediated ada expression in ADA deficient human hematopoietic progenitor cells. Proceedings of the National Academy of Science. 86:p.6748, 1989. |
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Laver J, Aboud M, Gasparetto C, Gillio A, Smith C, O'Reilly RJ, and Moore MAS. Effects of IL-1 on Hematopoietic recovery after myelosuppressive chemotherapy. Biotherapy. 1:p.293, 1989. |
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Gasparetto C, Laver J, Aboud M, Gillio A, Smith C, O'Reilly RJ, Moore, MAS. Effects of IL-1a on Hematopoietic progenitors: evidence of stimulatory and inhibitory activities in a primate model. Blood. 72:p.547, 1989. |
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Chinault AC, Blakesley VA, Roessler E, Willis DG, Smith C, Cook RG, Fenwick RG. Characterization of transferable plasmids from Shigella flexnerii 2a that confer resistance to trimethoprim, streptomycin and sulfonamides. Plasmid. 15:p.119, 1986. |
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Elwood, N, Jiang, XR, Chiu, CP, Lebkowski, J, Smith, C. Enhanced long term survival but no increased replicative capacity following retroviral transduction of cord blood CD34+ cells with hTERT. Hematologica. . |
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